Spinal Muscular Atrophy

Spinal Muscular Atrophy Spinal Muscular Atrophy Spinal muscular Atrophy is a disorder when the spine and muscles are affected. The Neurons on the spinal cord that control movement of muscles are infected and causes the Neurons to shrink and become destroyed and prevents messages coming from the body To the brain and muscles depend on that for proper function. Some muscles are not affected when having SMA like the bladder muscles. Hearing and vision are not affected and intelligence is normal or above average. Investigators have noted that children with SMA can have very high intelligence. There are 3 types of SMA all 3 types are known As autonomic recessive genes. To inherit SMA both parents must give the defective gene in order for the offspring to inherit the disorder. Sometimes SMA is inherited as an autonomic dominant gene. Type 1, 2, and 3 are got from a defected same gene on chromosome #5, different affected chromosomes will have different affects and types of SMA.There is another form of the disease called x-linked spinal bulbar atrophy that arises from a defect in a gene called the androgen receptor gene on the X chromosome. Every form of SMA affects the bones muscles of the trunk and limbs. These muscles are closer to the center of the body and are more infected than other parts that are farther than the body like the fingers. SMA type 1 affects the neurons that control your mouth and throat which makes chewing and eating problems. Type 1 is the most severe of all the types of SMA and is noticed during the first 6 months of birth. Cannot sit without support or a cushion, death is usually occurred before the age of 2. SMA type 2 isnt as worse as type 1 and is noticed during the ages of 7 months to 18 months of age. Cannot sit properly without a cushion or support, cannot learn to walk without any help or assistance has numerous swallowing difficulty some lucky children survive until childhood. Type 3 SMA occurs after the age of 18 months old. Weakness of the muscles in the mouth and throat is not likely to happen. Not as severe as type 1 and 2 but still can cause death if not cared for, children might live up to adulthood SMA is inherited by both parents having the recessive gene is their DNA and the offspring inherits 22 of the non sex chromosomes. When genes are defected they do not function and properly produce the proteins that are needed for a cell to function. A big chain can happen when a little protein is absent when there is too little or too much protein or if it doesnt work right for some reason. In the case of SMA protein abnormalities prevent the normal functioning of motor neurons. SMA causes muscle degeneration and will shrink until muscle weakness happens. SMA is not spreadable because disorders cannot spread from person to person only if parents have the 2 recessive SMA genes. There are no cures or treatments for spinal muscular atrophy right now but researchers and scientist are trying to find a way to get rid of SMA or at least reverse some of the affects that causes death for the young. Some symptoms of SMA are muscle weakness, leg weakness, thin muscles, hard time breathing, hard time eating/swallowing, lack of movement and walking, head control, hard time sitting up, hard time crawling when a baby. SMA affects life span a lot, especially when a child or a baby because you have a high risk of dying because of the disorder. Muscles are weak and have a hard time walking. SMA affects all kinds of people. In 1890 G. Werdnig found about SMA and the first type of the form of SMA. Years later a person named Kugelberg and another person named Welander described the less severe types of SMA and its affects to the human body and muscles. SMA is the most common diagnosis in girls with progressive weakness. It is one of the most common genetic causes of death in children! In the United States it is about 5 out of 100,000 child births that are affected with SMA. In ND (North Dakota) it is about 15 out of 100,000 children that are affected with SMA. SMA seems to be affecting more people in North Dakota then anywhere else in other areas. Males are more common to get SMA other than females, the ratio to males to females is 2:1 although the ratio is 2:1 how long you live with SMA is not affected by sex. Spinal muscular atrophy used to be only affecting black African Americans but years have passed and it is indicated that SMA is not affecting African Americans that much as it used to a while back. Spinal muscular atrophy is caused by the region of chromosome #5 that contains SMN (survival motor neuron) gene has a very abnormal huge duplication. The gene copies its self which causes mutation. The smn2 gene has a another mutation that makes less protein that does it in a very slow level. The most common forms of SMA are caused by the mutation of the SMN gene and affects different areas of the body and makes severe or less severe damages depending on how the gene mutates. Boys that get the gene die before the age of 2, but girls that get the gene are carriers unless they die before having an offspring. There are about 1,386 families that have SMA and 759 females and 776 males that do have SMA. Doctors and researches help with the symptoms and features of SMA to help reduce the chance of death. Doctors talk with children and help babies walk and breath. The spine is dislocated and is not straight. The spine wont function correctly and spine neurons will eventually die out and muscles will die out to.

Dramatic devices in ‘An Inspector Calls’ Essay

J.B Priestly presents his play ‘An Inspector Calls’ with contrasting views of responsibility and guilt within the Birling family and the Inspector. He utilizes a variety of dramatic devices throughout the play to create tension between the characters. One of the many dramatic devices he applies is when the Birling family are interrupted by an inspector while having a celebration. Inspector Goole is a firm socialist, he strongly believes wealth should be shared equally between all people, for example Eva Smith. He sticks up for the poorer classes rights to freedom of life. I suggest Priestly communicates his views through the character of the Inspector as he has fixed feelings about fairness and equality of everyone. He states ‘With privileges comes responsibility’ showing the understanding of those who are well to do should take responsibility for those who are less fortunate. The Inspector is a powerful character in this play. He intimidates the Birling family and makes them seem dense. â€Å"He speaks carefully, weightily and has a disconcerting habit of looking hard at the person he addresses before actually speaking.† He looks sternly in to their eyes before interrogating them. This makes the characters feel insecure and agitated, giving the impression of being responsible or guilty of something. Goole is very confident and can come across naive. He speaks like he knows everything about the Birling family and tries to drain the truth out of them. This shows the inspector has a function within the Birling household, he is there to make the family realise they need to take responsibility for their actions. He shows a contrasting view of responsibility to what the family believe. They don’t consider taking responsibility as must. Goole displays no emotion and is calm throughout the whole play. When Mrs Birling says â€Å"you seem to have made a great impression on this child† He replies â€Å"coolly† and also â€Å"the inspector will take offence† He responds â€Å"cutting in calmly† Where as Mr Birling becomes very distraught towards the inspector and wants to receive a reaction from him. He sharply informs the Inspector â€Å"I Don’t like that tone† I imply Birling doesn’t think responsibility is something that he should require within him. But Shelia is diverse she is very distressed. Her character develops into disturbance when the inspector reveals the news about Eva’s death. She illustrates remorse towards Eva, by projecting responsibility and becoming saddened. Shelia is one of the few characters in this play who takes responsibility for her actions. She realises they have to change their attitude in life and tries to convince her parents, but doesn’t succeed. â€Å"The point is, you don’t seem to of learnt anything† â€Å"it doesn’t much matter who it was who made us confess† (flaring up) â€Å"between us we drove that girl to commit suicide† The inspector takes control of the pace, he demonstrate leadership within the Birling family, taking one query at a time. â€Å"Massively taking charge† Priestly does this to keep the audience on their toes, creating apprehension. This is another dramatic device in its self. Priestly interoperates the opposite views in the characters of Mr Birling and Inspector Goole. They are both dominant and prevailing. Mr Birling tries to take power of his home but Goole is much more controlling and takes power of the event. This shows there is a battle between the two. Mr Birling is a capitalist, he judges that man should look after himself and take no responsibility for others. This proposes he’s a selfish person and is out for himself only. He articulates â€Å"you’d think everybody has to look after everybody else.† This implies he is highly against socialism and refuses to take responsibility for his community. Mr Birling is extremely unaware of the consequences he will suffer for the reason of his self indulgent attitude. He likes to impress people, â€Å"I speak as a hard headed business man who has to take risks and know what he’s about†. He expresses his thoughts with no consideration, to determine how he assumes how important and dependable he is. But the Inspector presents Birling as if he has no importance to the community. He interrupts Mr Birling and his speeches numerous times. When Birling states â€Å"that a man has to mind his own business and look after himself and his own – and-† Priestley creates a dramatic devise by generating sound. â€Å"There was a sharp ring of the door bell† I propose he does this to confirm how self absorbed Mr Birling and his speeches are, or how he judges what Birling utters is erratic and immoral. The inspector physically challenges Mr Birling’s beliefs about responsibility using these interrupting sounds. Throughout this play Mr Birling doesn’t change his beliefs, his attitude and nor his actions. He refuses to take responsibility for what he had done to Eva’s life, how he began the chain of events leading to Eva’s tragic death. I believe Priestly formed a domino effect in these events, one leading to another, until the final stage, with Eva’s life at the finishing point. I suggest Mr Birling is set in his ways; he has just the one view of everything, a selfish view. He chooses his views to evolve them around himself and his life, trying to make himself more important. He desires people to think of him as a leader, a role model. He wishes they where devoted to him. On the other hand, Shelia’s attitude and actions change drastically towards the end of the play. At the beginning she was a spoilt child but now she has become a young woman. She realises, unlike her father, that everybody has responsibilities. She is the key character that is moral with the most truth and decency; she faces the facts and knows she has to change her behaviour. But she is ashamed of her parents and concerned they won’t. â€Å"I remember what he said, how he looked and how he made me feel. Fire and blood and anguish, and it frightens me the way you talk.† This gives me an impression of Hell; this is why Shelia is changing, she doesn’t want to repeat the dreadful experience she has had that evening. I imply J.B Priestley’s point in this play â€Å"An inspector calls† is People need to realise they have to change their attitude towards general things in life or people will suffer consequences.

Allergies Involving Children

Allergies Some children have food allergies which means that they cannot tolerate certain foods and they may become very ill which may lead to going into anaphylactic shock if they eat certain foods. Some children are allergic to nuts or eggs and it is very important to make sure these foods are avoided which means checking the ingredients of some food products very carefully as every small amount can cause problems for allergic children and also some medical conditions can be cause by a child’s diet e. g. ood additives can affect the behaviour of some children with Attention Defiat Hyperactivity Disorder. Common food intolerances are:- Lactose – This is found in milk and dairy products Histamine – This is found in strawberries and ripe tomatoes. Tartrazine – This is mainly found in yellow food colouring, some drinks and sweets. Establishing different dietary requirements in your placement can be done by referring to the child’s parent, referring to the child’s record, speak to the children and referring to the other practitioners in your setting.Point which need to be considered are procedures, insurance, first aiders, allergies, photos in medical records, staff awareness, trained staff for administering medication and close contact with parents. Children with different dietary needs In a childcare setting you will encounter children with different dietary needs which are important because you may need to understand what can affect a Childs dietary requirements. Medical ConditionsMedical conditions can affect a child’s diet in the following ways:- Diabetes which means that the pancreas cannot regulate the body’s sugar levels and children will need to avoid sugar but should have regular meals and snacks and also each child’s needs will be different and you will have to work closely with your supervisor and the child’s parent to support a diabetic child. Coeliac disease means that children can not absorb their food normally and will need to avoid gluten which is mainly found in cerals such as wheat and barley and coeliac disease is usually detected after a child has been weaned from breast milk.Food Preferences Vegetarians do not eat meat, fish or any other products which come from animals such as milk, eggs and cheese. Also if children follow a vegetarian or vegan diet then special care must be taken to make sure all the essential nutrients are included in their diet. All children in your care must be able to eat and drink safely so that food poisoning or related illnesses are avoided and also bacteria can grow quickly on food and your role in handling food and drink appropriately is essential and you will need to understand how to store, prepare and serve food.Establish Different dietary requirements of children and young people There are various dietary requirements that you need to consider to meet the different needs of children which include religious, cultural, all ergies, health requirements and individual choices or preferences. Religious and cultural Muslims – * Eat halal meat, fish, shell fish which is slaughtered and is prepared in a certain way. * Do not eat pork or dairy products that contain rennet which is curdled milk from the stomach of an unweaned. * Fast during Ramadan Jews- Do not eat dairy products with meat * Eat kosher lamb, beef and chicken which is slaughtered and prepared in a certain way. * Fast during Yorn Kippur * Fish should have fins, scales and backbones. Sikhs- * Do not eat beef as the cow is a sacred animal. * Some Sikhs may eat chicken, cheese, fish and shell fish. * Rarely eat pork Hindus * Do not eat meat as the cow is seen as a scared animal. * Do not eat dairy products that contain rennet * Usually vegetarian * Eat fish with fin and scales Rastafarians * Do eat lamb (some do) beef and chicken but do not eat shellfish.

How to Write a Winning Analysis Essay

How to Write Analysis Essay